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Japanese and Korean patients have experienced much higher incidence and mortality rates when using tumor necrosis factor TNF and methotrexate.

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Allopurinol is called for when you have had more than one attack of gout in a year, when you have hyperuricemia with kidney stones associated with your gout, when uricosurics (see above) have failed to maintain appropriate serum urate levels, when you are allergic or intolerant of uricosuric agents, when you have tophaceous gout, or as prophylaxis against kidney damage from uric acid crystals in patients on cancer chemotherapy.

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Clear, noncoated catheters are the most costeffective, but other options also should be offered and considered.

The treatment regimen needs to be tailored to the severity and extent of disease in each individual patient.

Some case reports suspect it of causing liver disease.

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You can visit the ACR to learn more about this important bill and other issues facing rheumatologists, and to send a message to your member asking that they support the Flex-IT Act.

It is important to remember that gout attacks can resolve very quickly (within hours) if treatment is started very early after onset.

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SOURCE: Creighton University, news release, Jan.

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Congress, the reality is that the FDA has not, to this day, issued any further statements on the subject.

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Disclosures: Eckel reports ties to Novo Nordisk.

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His insights, which lead to antibiotics, hygiene, and vaccines have undoubtedly prevented more morbidity and mortality than any human in history.

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