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The reviewers sought to include randomized controlled trials (RCTs) and comparative observational studies enrolling women with polycystic ovary syndrome (PCOS) who received metformin (Mt), oral contraceptive pills (OCPs), or antiandrogen agents (AAs) for at least 6 months and reported any severe adverse effects.

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Aromasin is not approved by the FDA to be given as monotherapy, but many doctors use it this way.

Possible harms from taking aromatase inhibitors include muscle and pain, osteoporosis, hot flashes, and feeling very tired.

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They may also be used to reduce increase of estrogen conversion during cycle with external testosterone.

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Among young women under 21 who chose the pill, the patch or vaginal ring, the risk of unintended pregnancy is almost twice as high as that for older women.

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Zoledronate has shown significant benefits versus placebo over three years, with a reduced number of and improved markers of bone density.

Also, is there anyone in the field who researches these side effects or who has more experience managing them?

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Thirty women (18 in the letrozole group and 12 in the placebo group) who did not have investigation forms at base line were excluded from the analyses.

These side effects in most individuals are accompanied by signs and symptoms of hypoestrogenism.

Since the 1960s, tamoxifen (Nolvadex) has been prescribed for women with ER-positive breast cancer to reduce the risk of cancer in the opposite breast.

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Organizations including the American Cancer Society, the American College of Obstetricians and Gynecologists, and the National Comprehensive Cancer Network recommend that women with an average risk for breast cancer have their first screening mammogram at age 40.

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